Search results for " dimethylsulfoxide"

showing 10 items of 33 documents

CCDC 751046: Experimental Crystal Structure Determination

2010

Related Article: J.Vicente, I.Saura-Llamas, J.Turpin, D.Bautista, C.R.de Arellano, P.G.Jones|2009|Organometallics|28|4175|doi:10.1021/om9002895

(eta^2^-4-(2-(Aminomethyl)-5-chlorophenyl)-1234-tetraphenylbuta-13-dien-1-yl)-(bromo)-palladium dimethylsulfoxide solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 164934: Experimental Crystal Structure Determination

2001

Related Article: H.Grove, J.Sletten, M.Julve, F.Lloret|2001|J.Chem.Soc.,Dalton Trans.||2487|doi:10.1039/b103588f

(mu2-23-bis(2-Pyridyl)pyrazine-NN'N''N''')-aqua-tetrachloro-(dimethylsulfoxide-O)-di-copper(ii) dimethylsulfoxide solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 152579: Experimental Crystal Structure Determination

2001

Related Article: M.J.Krische, J.-M.Lehn, N.Kyritsakas, J.Fischer, E.K.Wegelius, K.Rissanen|2000|Tetrahedron|56|6701|doi:10.1016/S0040-4020(00)00489-0

910-bis(2-Aminopyrimidin-5-yl)anthracene perchloroethene dimethylsulfoxide clathrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Synthesis, spectroscopic characterization and antiproliferative activity of two platinum(II) complexes containing N-donor heterocycles

2014

Abstract Novel mononuclear complexes of Pt(II), cis -[PtCl 2 (DMSO)HL]·2DMSO ( 1 ), where HL = 7-amino-2-(methylthio)[1,2,4]triazolo[1,5- a ]pyrimidine-6-carboxylic acid and Pt(bdt)Cl 2 ( 2 ), where bdt = [2,4-bis(5,6-diphenyl-1,2,4-triazin-3yl)-pyridine] have been synthesized and characterized by elemental analysis, IR and 1 H NMR spectroscopy and X-ray crystallography diffraction analyses. The molecular structure of ( 1 ) shows that Pt(II) ion has a square planar geometry with N(3) bonded heterocycle ligand, two cis chloride anions and S-bonded dimethylsulfoxide. The antiproliferative activity of complexes ( 1 ) and ( 2 ) has been tested in vitro against HepG2 human hepatoma cells and non…

CisplatinLigandChemistryStereochemistrychemistry.chemical_elementPhosphatidylserineIn vitroMononuclear platinum complexes Heterocyclic nitrogen Dimethylsulfoxide Antitumor activityAntitumor activity Dimethylsulfoxide Heterocyclic nitrogen Mononuclear platinum complexesDimethylsulfoxide Heterocyclic nitrogen Mononuclear platinum complexesInorganic Chemistrychemistry.chemical_compoundMembraneSettore CHIM/03 - Chimica Generale E InorganicaMaterials ChemistryProton NMRmedicineMoleculePhysical and Theoretical ChemistryPlatinumAntitumor activitymedicine.drugInorganica Chimica Acta
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The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats

2017

Hyperglycemia associated with inflammation and oxidative stress is a major cause of vascular dysfunction and cardiovascular disease in diabetes. Recent data reports that a selective sodium-glucose co-transporter 2 inhibitor (SGLT2i), empagliflozin (Jardiance®), ameliorates glucotoxicity via excretion of excess glucose in urine (glucosuria) and significantly improves cardiovascular mortality in type 2 diabetes mellitus (T2DM). The overarching hypothesis is that hyperglycemia and glucotoxicity are upstream of all other complications seen in diabetes. The aim of this study was to investigate effects of empagliflozin on glucotoxicity, β-cell function, inflammation, oxidative stress and endothel…

Male0301 basic medicineendocrine system diseasesDiabetic CardiomyopathiesFPS-ZM1 RAGE inhibitorClinical BiochemistryAorta ThoracicRAGE receptor for AGEICAM-1 intercellular adhesion molecule-1ECL enhanced chemiluminescence030204 cardiovascular system & hematologyDPP-4 dipeptidyl peptidase-4medicine.disease_causeTNF-α tumor necrosis factor-αBiochemistryeNOS endothelial •NO synthase (type 3)0302 clinical medicineGlucosidesecSOD extracellular superoxide dismutaseInsulin-Secreting CellsCCL-2 see MCP-1HyperlipidemiaHyperinsulinemiaGTN glyceryl trinitrate (nitroglycerin)IFN-γ interferon-γDHE dihydroethidineEndothelial dysfunctionEndothelial dysfunctionIL-6 interleukin-6lcsh:QH301-705.5HO-1 heme oxygenase-1lcsh:R5-920ICAM-1NG normoglycemiaDiabetesNox catalytic subunit of NADPH oxidaseSGLT2 inhibitorβ-cell contentL-012 8-amino-5-chloro-7-phenylpyrido[34-d]pyridazine-14-(2H3H)dione sodium saltChIP chromatin immunoprecipitationC-Reactive ProteinCRP C-reactive proteinAGE advanced glycation end productsHbA1c glycohemoglobinlcsh:Medicine (General)Research PaperZucker diabetic fatty ratsmedicine.medical_specialtyDMSO dimethylsulfoxideMCP-1 monocyte-chemoattractant-protein-1qRT-PCR quantitative reverse transcription polymerase chain reactionZDF Zucker diabetic fatty (rat)Low-grade inflammation03 medical and health sciencesROS reactive oxygen speciesSodium-Glucose Transporter 2Physiology (medical)Internal medicineDiabetes mellitusPKC protein kinase CEmpagliflozinmedicineAnimalsHypoglycemic AgentsBenzhydryl CompoundsCOX2 cyclooxygenase-2SGLT2i SGLT2 inhibitorSodium-Glucose Transporter 2 InhibitorsGlycated HemoglobinACh acetylcholinebusiness.industryOrganic Chemistrynutritional and metabolic diseasesType 2 Diabetes Mellitusmedicine.diseaseH2K9me2 histone3 lysine9 dimethylationRatsRats ZuckerDHFR dihydrofolate reductaseSGLT2 sodium-glucose co-transporter-2Oxidative StresssGC soluable guanylyl cyclaseGlucose030104 developmental biologyEndocrinologylcsh:Biology (General)ALDH-2 mitochondrial aldehyde dehydrogenaseEndothelium VascularAGE/RAGE signalingHG hyperglycemiabusinessOxidative stressRedox Biology
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CCDC 885911: Experimental Crystal Structure Determination

2013

Related Article: A.Suhonen, E.Nauha, K.Salorinne, K.Helttunen, M.Nissinen|2012|CrystEngComm|14|7398|doi:10.1039/c2ce25981h

N2N6-bis(2-benzamidophenyl)pyridine-26-dicarboxamide dimethylsulfoxide solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 778753: Experimental Crystal Structure Determination

2010

Related Article: D.Meshcheryakov, M.Bolte, V.Bohmer|2010|Tetrahedron Lett.|51|1202|doi:10.1016/j.tetlet.2009.12.087

Space GroupCrystallography10H22H-Tetrabenzo[bgjo][19461214]dioxatetra-azacyclohexadecine-1123(12H24H)-dione dimethylsulfoxide solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 204644: Experimental Crystal Structure Determination

2005

Related Article: M.Luostarinen, A.Ahman, M.Nissinen, K.Rissanen|2004|Supramol.Chem.|16|505|doi:10.1080/10610270410001729748

Space GroupCrystallography2814202632-Hexaethyl-456101112161718222324282930343536-octadecahydroxycalix(6)arene dimethylsulfoxide clathrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 633847: Experimental Crystal Structure Determination

2007

Related Article: M.Albrecht, Triyanti, S.Schiffers, O.Osetska, G.Raabe, T.Wieland, L.Russo, K.Rissanen|2007|Eur.J.Org.Chem.|2007|2850|doi:10.1002/ejoc.200700130

Space GroupCrystallography4-Isobutoxy-8-(3-phenylureido)quinoline-2-carboxylic acid phenyl amide dimethylsulfoxide solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 667519: Experimental Crystal Structure Determination

2008

Related Article: D.Meshcheryakov, F.Arnaud-Neu, V.Bohmer, M.Bolte, V.Hubscher-Bruder, E.Jobin, I.Thondorf, S.Werner|2008|Org.Biomol.Chem.|6|1004|doi:10.1039/b718114k

Space GroupCrystallographyCrystal System333-Di-t-butyl-3737-dimethyl-5H17H29H-135-methanohexabenzo[bgjorw][19174612142022] trioxahexaazacyclotetracosine-61830(7H19H31H)-trione dimethylsulfoxide methanol solvateCrystal StructureCell ParametersExperimental 3D Coordinates
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